Xuming ZhangBoard Advisor

    Prof. Xuming Zhang (VMD, Ph.D.) in the Department of Microbiology and Immunology at UAMS (Little Rock, AR), a world pioneer in Molecular Biology and Pathogenesis of Coronaviruses, started to study coronaviruses in 1989 and to publish papers in 1991[1],[2],[3]. He was the world-first to report in 1994 the first evidence of animal-targeting coronavirus transferring to human[4], which gained much doubt first and then worldwide appreciations in 2003 when the SARS pandemic in China proved his 1994 finding. He uses animal- and human-targeting coronaviruses and flu viruses in the BSL-2 and BSL-3 labs to develop with Prof. Ryan Tian (UARK) new methods for diagnosing COVID-19, screening virucides and antibodies, testing new PPEs, etc.

    [1] Zhang, Xuming, Konstantin G. Kousoulas, and Johannes Storz. “The hemagglutinin/esterase gene of human coronavirus strain OC43: phylogenetic relationships to bovine and murine coronaviruses and influenza C virus.” Virology, 186(1), 318-323 (1991).
    [2] Zhang, Xuming, Konstantin G. Kousoulas, and Johannes Storz. “Comparison of the nucleotide and deduced amino acid sequences of the S genes specified by virulent and avirulent strains of bovine coronaviruses.” Virology, 183 (1), 397-404 (1991).
    [3] Johannes Storz, Xuming Zhang. “Infectious mechanisms of enteropathogenic bovine coronaviruses”. Behring Institute Mitteilungen, 89, 130-137 (1991).
    [4] Zhang, X. M., W. Herbst, K. G. Kousoulas, and J. Storz. “Biological and genetic characterization of a hemagglutinating coronavirus isolated from a diarrhoeic child”. Journal of Medical Virology, 44, 152–161 (1994).